Clinical dilemmas: beta-adrenoblockers in atherosclerosis

Beta-blockers are the cornerstone of treatment for various cardiovascular conditions. were discovered as antianginal drugs in 1960s and currently widely used heart failure, arrhythmias, ischemic disease. In this article, we review evidence beneficial effects beta-blockers these conditions, well current recommendations clinical practice guidelines their use. Surprisingly, despite having been prescribed more than 4 decades, new, previously unnoticed mechanisms action on cellular compartments still being discovered, which continues to open up new horizons All all, one most fascinating drug groups our therapeutic armamentarium.